Charlie Sheen

Jeffrey Cage

Whoopi Goldberg

Metzie

Luis Guzmán

Eddie

Gina Gershon

Eve

Wood Harris

Michael

Bruce Davison

Monohan

Dahlia Waingort

Lisa

Faune Chambers Watkins

Holly

Matt Lauer

Himself

Olga Fonda

Tina

Ian Fisher

Fireman

Jacqueline Bisset

Diane

Billy Malone

Anderson

Katie Couric

Herself

Ryan R. Johnson

Firefighter

Whitney Avalon

Nicki

April Betts

Waitress

Brian J. Singer

Frankie

Prestyn Bates

J.J.

James Quattrochi

Captain

Dave Cobert

Chief

Mandell Frazier

Paramedic

Nick Stellate

Firefighter

Matt Laydon

Commuter

Johnny Colon

Lopez

Sterling Fitzgerald

Executive

Paul David Roberts

Technician

Punnavith Koy

George W. Bush

Self (archive footage) (uncredited)